Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy

Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy

Abstract Backgrounds Sonodynamic therapy (SDT) as an emerging reactive oxygen species (ROS)-mediated antitumor strategy is challenged by the rapid depletion of oxygen, as well as the hypoxic tumor microenvironment. Instead of the presently available coping strategies that amplify the endogenous O2 l...

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Bibliographic Details
Main Authors: Weijuan Zou, Junnian Hao, Jianrong Wu, Xiaojun Cai, Bing Hu, Zhigang Wang, Yuanyi Zheng
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Subjects:
Sonodynamic therapy
Hypoxia regulation
Pro-death autophagy
Hollow mesoporous organosilica
Biodegradable
Online Access:https://doi.org/10.1186/s12951-021-01166-y

Internet

https://doi.org/10.1186/s12951-021-01166-y

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