One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate
The title compound, Methyl 5-Hydroxy-1-Phenyl-1H-Pyrazole-3-Carboxylate (C11H10N2O3), was prepared by a one-pot, two-component reaction of an equimolar mixture of phenyl hydrazine and dimethyl acetylene dicarboxylate (DMAD) at reflux temperature for 2 h in a mixture of toluene and dichloromethane as...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-08-01
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| Series: | Crystals |
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| Online Access: | http://www.mdpi.com/2073-4352/2/3/1248 |
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| author | Aamer Saeed Ifzan Arshad Ulrich Flörke |
| author_facet | Aamer Saeed Ifzan Arshad Ulrich Flörke |
| author_sort | Aamer Saeed |
| collection | DOAJ |
| description | The title compound, Methyl 5-Hydroxy-1-Phenyl-1H-Pyrazole-3-Carboxylate (C11H10N2O3), was prepared by a one-pot, two-component reaction of an equimolar mixture of phenyl hydrazine and dimethyl acetylene dicarboxylate (DMAD) at reflux temperature for 2 h in a mixture of toluene and dichloromethane as solvent. C11H10N2O3 was crystallized from an ethanol solution in monoclinic space group P21/c with unit cell dimensions a = 9.5408(16), b = 9.5827(16), c = 11.580(2) Å, β = 105.838(3)°, V = 1018.5(3) Å3, Z = 4. |
| first_indexed | 2024-04-14T01:29:57Z |
| format | Article |
| id | doaj.art-63ce87c769d74c62bec1c42b7a12c511 |
| institution | Directory Open Access Journal |
| issn | 2073-4352 |
| language | English |
| last_indexed | 2024-04-14T01:29:57Z |
| publishDate | 2012-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Crystals |
| spelling | doaj.art-63ce87c769d74c62bec1c42b7a12c5112022-12-22T02:20:13ZengMDPI AGCrystals2073-43522012-08-01231248125210.3390/cryst2031248One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylateAamer SaeedIfzan ArshadUlrich FlörkeThe title compound, Methyl 5-Hydroxy-1-Phenyl-1H-Pyrazole-3-Carboxylate (C11H10N2O3), was prepared by a one-pot, two-component reaction of an equimolar mixture of phenyl hydrazine and dimethyl acetylene dicarboxylate (DMAD) at reflux temperature for 2 h in a mixture of toluene and dichloromethane as solvent. C11H10N2O3 was crystallized from an ethanol solution in monoclinic space group P21/c with unit cell dimensions a = 9.5408(16), b = 9.5827(16), c = 11.580(2) Å, β = 105.838(3)°, V = 1018.5(3) Å3, Z = 4.http://www.mdpi.com/2073-4352/2/3/1248pyrazolemethyl 5-hydroxy-1-phenyl-1H-pyrazole-3-carboxylatecrystal structure |
| spellingShingle | Aamer Saeed Ifzan Arshad Ulrich Flörke One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate Crystals pyrazole methyl 5-hydroxy-1-phenyl-1H-pyrazole-3-carboxylate crystal structure |
| title | One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate |
| title_full | One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate |
| title_fullStr | One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate |
| title_full_unstemmed | One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate |
| title_short | One-Pot Synthesis and Crystal Structure of Methyl 5-Hydroxy-1-phenyl-1H-pyrazole-3-carboxylate |
| title_sort | one pot synthesis and crystal structure of methyl 5 hydroxy 1 phenyl 1h pyrazole 3 carboxylate |
| topic | pyrazole methyl 5-hydroxy-1-phenyl-1H-pyrazole-3-carboxylate crystal structure |
| url | http://www.mdpi.com/2073-4352/2/3/1248 |
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