Robust joint score tests in the application of DNA methylation data analysis

Abstract Background Recently differential variability has been showed to be valuable in evaluating the association of DNA methylation to the risks of complex human diseases. The statistical tests based on both differential methylation level and differential variability can be more powerful than thos...

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Bibliographic Details
Main Authors: Xuan Li, Yuejiao Fu, Xiaogang Wang, Weiliang Qiu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2185-3