PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases.

Susceptibility loci identified by GWAS generally account for a limited fraction of heritability. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limited practical use. Many methods have been developed to overcome these limitations by incorp...

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Bibliographic Details
Main Authors: Marzieh Ayati, Mehmet Koyutürk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5105987?pdf=render