CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract

CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract

Characteristic of allergic asthma, CD4+Th2 lymphocytes secrete Th2 cytokines, interleukin (IL)-4, IL-13, and IL-5 that mediate the inflammatory immune response. Surface expression of CD2 and its ligand, CD58, is increased on the monocytes and eosinophils of asthma patients, which correlate with elev...

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Bibliographic Details
Main Authors: Tanwir Hashem, Ananth K. Kammala, Kanedra Thaxton, Ryan M. Griffin, Kellie Mullany, Reynold A. Panettieri, Hariharan Subramanian, Rupali Das
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
asthma
Th2-allergic response
house dust mite extract
costimulatory molecules
CD2
interleukin (IL)-13
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00881/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00881/full

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