A Capillary Electrophoresis-Based Method for the Measurement of Hydroxychloroquine and Its Active Metabolite Desethyl Hydroxychloroquine in Whole Blood in Patients with Rheumatoid Arthritis

A Capillary Electrophoresis-Based Method for the Measurement of Hydroxychloroquine and Its Active Metabolite Desethyl Hydroxychloroquine in Whole Blood in Patients with Rheumatoid Arthritis

A capillary electrophoresis method was developed to detect and measure hydroxychloroquine (HCQ) and its active metabolite desethyl hydroxychloroquine (DHCQ) in whole blood in patients with rheumatoid arthritis. The best separation in terms of peak area reproducibility, migration time, peak shape, an...

Full description

Bibliographic Details
Main Authors: Salvatore Sotgia, Angelo Zinellu, Nicola Mundula, Arduino A. Mangoni, Ciriaco Carru, Gian Luca Erre
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
disease-modifying anti-rheumatic drug
autoimmune diseases
capillary electrophoresis
4-aminoquinoline derivative
hydroxychloroquine
desethylhydroxychloroquine
Online Access:https://www.mdpi.com/1420-3049/27/12/3901

Internet

https://www.mdpi.com/1420-3049/27/12/3901

Similar Items