Transcriptome combined with Mendelian randomization to screen key genes associated with mitochondrial and programmed cell death causally associated with diabetic retinopathy

Transcriptome combined with Mendelian randomization to screen key genes associated with mitochondrial and programmed cell death causally associated with diabetic retinopathy

BackgroundMitochondrial dysfunction in the retina can induce apoptosis of retinal capillary cells, leading to diabetic retinopathy (DR). This study aimed to explore key genes related to programmed cell death (PCD) and mitochondria in DR via bioinformatic analysis.MethodsA differential analysis was p...

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Bibliographic Details
Main Authors: Shule Jiang, Xuemei Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Endocrinology
Subjects:
diabetic retinopathy
immune infiltration
Mendelian randomization
programmed cell death
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1422787/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1422787/full

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