Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog
The underlying functional and molecular changes in canine primary uterine inertia (PUI) are still not clarified. Leptin (Lep) and obesity negatively affect uterine contractility in women, partly mediated by the RhoA/Rho associated kinase pathway, affecting myometrial calcium sensitization. We hypoth...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Society for Reproduction and Development
2021-03-01
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Series: | The Journal of Reproduction and Development |
Subjects: | |
Online Access: | https://www.jstage.jst.go.jp/article/jrd/67/3/67_2020-141/_pdf/-char/en |