Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog

Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog

The underlying functional and molecular changes in canine primary uterine inertia (PUI) are still not clarified. Leptin (Lep) and obesity negatively affect uterine contractility in women, partly mediated by the RhoA/Rho associated kinase pathway, affecting myometrial calcium sensitization. We hypoth...

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Bibliographic Details
Main Authors: Bianca Lourdes FREHNER, Iris Margaret REICHLER, Mariusz Pawel KOWALEWSKI, Aykut GRAM, Stefanie KELLER, Sandra GOERICKE-PESCH, Orsolya BALOGH
Format: Article
Language:English
Published: The Society for Reproduction and Development 2021-03-01
Series:The Journal of Reproduction and Development
Subjects:
canine
contractility
dystocia
parturition
uterus
Online Access:https://www.jstage.jst.go.jp/article/jrd/67/3/67_2020-141/_pdf/-char/en

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