Comprehensive Characterization of the Mutational Landscape in Localized Anal Squamous Cell Carcinoma

Anal squamous cell carcinoma (ASCC) is a rare neoplasm. Chemoradiotherapy is the standard of care, with no therapeutic advances achieved over the past three decades. Thus, a deeper molecular characterization of this disease is still necessary. We analyzed 46 paraffin-embedded tumor samples from pati...

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Main Authors: Lucía Trilla-Fuertes, Ismael Ghanem, Joan Maurel, Laura G-Pastrián, Marta Mendiola, Cristina Peña, Rocío López-Vacas, Guillermo Prado-Vázquez, Elena López-Camacho, Andrea Zapater-Moros, Victoria Heredia, Miriam Cuatrecasas, Pilar García-Alfonso, Jaume Capdevila, Carles Conill, Rocío García-Carbonero, Karen E. Heath, Ricardo Ramos-Ruiz, Carlos Llorens, Ángel Campos-Barros, Angelo Gámez-Pozo, Jaime Feliu, Juan Ángel Fresno Vara
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319306746