Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits

Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits

Cholesteryl ester transfer protein (CETP) inhibitors increase high density lipoprotein-cholesterol (HDL-C) in animals and humans, but whether CETP inhibition will be antiatherogenic is still uncertain. We tested the CETP inhibitor torcetrapib in rabbits fed an atherogenic diet at a dose sufficient t...

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Bibliographic Details
Main Authors: Lee A. Morehouse, Eliot D. Sugarman, Patricia-Ann Bourassa, Thomas M. Sand, Francesca Zimetti, Feng Gao, George H. Rothblat, Anthony J. Milici
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester transfer protein
cholesterol efflux
reverse cholesterol transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425544

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http://www.sciencedirect.com/science/article/pii/S0022227520425544

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