A yeast chemogenomic screen identifies pathways that modulate adipic acid toxicity

Summary: Adipic acid production by yeast fermentation is gaining attention as a renewable source of platform chemicals for making nylon products. However, adipic acid toxicity inhibits yeast growth and fermentation. Here, we performed a chemogenomic screen in Saccharomyces cerevisiae to understand t...

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Bibliographic Details
Main Authors: Eugene Fletcher, Kevin Mercurio, Elizabeth A. Walden, Kristin Baetz
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002959