Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth

Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth

Abstract Discogenic pain is associated with deep nerve ingrowth in annulus fibrosus tissue (AF) of intervertebral disc (IVD). To model AF nerve ingrowth, primary bovine dorsal root ganglion (DRG) micro‐scale tissue units are spatially organised around an AF explant by mild hydrodynamic forces within...

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Bibliographic Details
Main Authors: Junxuan Ma, Janick Eglauf, Sibylle Grad, Mauro Alini, Tiziano Serra
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
acoustic assembly
advanced in vitro models
alternatives to animal testing
multicellular system
sensory nerve ingrowth
Online Access:https://doi.org/10.1002/advs.202308478

Internet

https://doi.org/10.1002/advs.202308478

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