Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity.

Accumulating evidence indicates that metabolic dysfunction with visceral obesity is a major medical problem associated with the development of hypertension, type 2 diabetes (T2DM) and dyslipidemia, and ultimately severe cardiovascular and renal disease. Therefore, an effective anti-obesity treatment...

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Bibliographic Details
Main Authors: Kengo Azushima, Kouichi Tamura, Hiromichi Wakui, Akinobu Maeda, Masato Ohsawa, Kazushi Uneda, Ryu Kobayashi, Tomohiko Kanaoka, Toru Dejima, Tetsuya Fujikawa, Akio Yamashita, Yoshiyuki Toya, Satoshi Umemura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3794018?pdf=render