ATZ11 recognizes not only Z-α1-antitrypsin-polymers and complexed forms of non-Z-α1-antitrypsin but also the von Willebrand factor.

AIMS: The ATZ11 antibody has been well established for the identification of α1-anti-trypsin (AAT) molecule type PiZ (Z-AAT) in blood samples and liver tissue. In this study, we systematically analyzed the antibody for additional binding sites in human tissue. METHODS AND RESULTS: Ultrastructural AT...

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Main Authors: Diane Goltz, Kanishka Hittetiya, Hamideh Yadegari, Julia Driesen, Jutta Kirfel, Thomas Neuhaus, Susanne Steiner, Christiane Esch, Jörg Bedorf, Hans-Jörg Hertfelder, Hans-Peter Fischer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960128?pdf=render