High-glucose inhibits human fibroblast cell migration in wound healing via repression of bFGF-regulating JNK phosphorylation.

High-glucose inhibits human fibroblast cell migration in wound healing via repression of bFGF-regulating JNK phosphorylation.

One of the major symptoms of diabetes mellitus (DM) is delayed wound healing, which affects large populations of patients worldwide. However, the underlying mechanism behind this illness remains elusive. Skin wound healing requires a series of coordinated processes, including fibroblast cell prolife...

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Bibliographic Details
Main Authors: Yuan Hu Xuan, Bin Bin Huang, Hai Shan Tian, Li Sha Chi, Yuan Meng Duan, Xi Wang, Zhong Xin Zhu, Wan Hui Cai, Yu Ting Zhu, Tie Min Wei, Hong Bo Ye, Wei Tao Cong, Li Tai Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4171528?pdf=render

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http://europepmc.org/articles/PMC4171528?pdf=render

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