Yeast Bax Inhibitor (Bxi1p/Ybh3p) Is Not Required for the Action of Bcl-2 Family Proteins on Cell Viability

Yeast Bax Inhibitor (Bxi1p/Ybh3p) Is Not Required for the Action of Bcl-2 Family Proteins on Cell Viability

Permeabilization of mitochondrial membrane by proteins of the BCL-2 family is a key decisive event in the induction of apoptosis in mammalian cells. Although yeast does not have homologs of the BCL-2 family, when these are expressed in yeast, they modulate the survival of cells in a way that corresp...

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Bibliographic Details
Main Authors: Marek Mentel, Miroslava Illová, Veronika Krajčovičová, Gabriela Kroupová, Zuzana Mannová, Petra Chovančíková, Peter Polčic
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
yeast
<i>Saccharomyces cerevisiae</i>
apoptosis
endoplasmic reticulum
Bcl-2 family
regulated cell death
Online Access:https://www.mdpi.com/1422-0067/24/15/12011

Internet

https://www.mdpi.com/1422-0067/24/15/12011

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