Melanotic Neuroectodermal Tumor of Infancy (MNTI) and Pineal Anlage Tumor (PAT) Harbor A Medulloblastoma Signature by DNA Methylation Profiling

Melanotic Neuroectodermal Tumor of Infancy (MNTI) and Pineal Anlage Tumor (PAT) Harbor A Medulloblastoma Signature by DNA Methylation Profiling

MNTI is a rare tumor of indeterminate histogenesis and molecular signature. We performed methylation and copy number variation (CNV) profiles in patients with MNTI (<i>n</i> = 7) and PAT (<i>n</i> = 1) compared to the methylation brain tumor classifier v11b4 (BT-C) and the me...

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Bibliographic Details
Main Authors: Oscar Lopez-Nunez, Rita Alaggio, Ivy John, Andrea Ciolfi, Lucia Pedace, Angela Mastronuzzi, Francesca Gianno, Felice Giangaspero, Sabrina Rossi, Vittoria Donofrio, Giuseppe Cinalli, Lea F. Surrey, Marco Tartaglia, Franco Locatelli, Evelina Miele
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
melanotic neuroectodermal tumor
melanotic progonoma
medulloblastoma
pineal anlage tumor
DNA methylation
copy number variation
Online Access:https://www.mdpi.com/2072-6694/13/4/706

Internet

https://www.mdpi.com/2072-6694/13/4/706

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