<i>N</i>-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells—An In Vitro Model for Early Inflammatory Profiling of Schwann Cells

<i>N</i>-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells—An In Vitro Model for Early Inflammatory Profiling of Schwann Cells

Following nerve injury, disintegrated axonal mitochondria distal to the injury site release mitochondrial formylated peptides and DNA that can induce activation and inflammatory profiling of Schwann cells via formyl peptide receptor 2 (Fpr2) and toll-like receptor 9 (TLR9), respectively. We studied...

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Bibliographic Details
Main Authors: Andrea Korimová, Petr Dubový
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
Wallerian degeneration
mitochondria
disintegration
damage-associated molecular patterns
cytokines
chemokines
Online Access:https://www.mdpi.com/2073-4409/9/12/2661

Internet

https://www.mdpi.com/2073-4409/9/12/2661

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