Cyclodextrin–polysaccharide-based, in situ-gelled system for ocular antifungal delivery

Cyclodextrin–polysaccharide-based, in situ-gelled system for ocular antifungal delivery

Fluconazole was studied with two different hydrophilic cyclodextrins (hydroxypropyl-β-cyclodextrin (HPBCD) and sulfobutyl ether-β-cyclodextrin (SBECD)) for the formation of inclusion complexes. HPBCD and SBECD showed low cell cytotoxicity in human keratocytes as assessed by the label-free xCELLigenc...

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Bibliographic Details
Main Authors: Anxo Fernández-Ferreiro, Noelia Fernández Bargiela, María Santiago Varela, Maria Gil Martínez, Maria Pardo, Antonio Piñeiro Ces, José Blanco Méndez, Miguel González Barcia, Maria Jesus Lamas, Francisco.J. Otero-Espinar
Format: Article
Language:English
Published: Beilstein-Institut 2014-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
cyclodextrins
eye drops
fluconazole
hydroxypropyl-β-cyclodextrin
sulfobutylether-β-cyclodextrin
Online Access:https://doi.org/10.3762/bjoc.10.308

Internet

https://doi.org/10.3762/bjoc.10.308

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