Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma
Abstract Background Treatment with a combination of PD-1 and CTLA-4 targeted checkpoint inhibition has improved outcome of melanoma patients and led to durable remissions but is also associated with significant toxicities. Endocrinopathies such as thyroiditis and hypophysitis are often seen, but oth...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2019-02-01
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Series: | Journal for ImmunoTherapy of Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40425-019-0528-x |