Computation of Single-Cell Metabolite Distributions Using Mixture Models

Metabolic heterogeneity is widely recognized as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular events. However, metabolism has been traditionally viewed as...

Full description

Bibliographic Details
Main Authors: Mona K. Tonn, Philipp Thomas, Mauricio Barahona, Diego A. Oyarzún
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.614832/full