CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22

CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22

Dysregulation of interleukin-22 (IL-22) has been associated with autoimmune diseases but divergent effects upon inflammation have hampered efforts to define its contribution to pathogenesis. Here, we examined the role of IL-22 in patients with psoriatic arthritis (PsA). In the peripheral blood of Ps...

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Bibliographic Details
Main Authors: Amara Ezeonyeji, Helen Baldwin, Milica Vukmanovic-Stejic, Michael R. Ehrenstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
IL-22
interferon-gamma
naïve T cell
psoriatic arthritis
anti-TNF
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01403/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01403/full

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