Dexamethasone-Loaded Radially Mesoporous Silica Nanoparticles for Sustained Anti-Inflammatory Effects in Rheumatoid Arthritis

Dexamethasone-Loaded Radially Mesoporous Silica Nanoparticles for Sustained Anti-Inflammatory Effects in Rheumatoid Arthritis

Radially mesoporous silica nanoparticles (RMSNs) with protonated amine functionality are proposed to be a dexamethasone (Dex) carrier that could achieve a sustained anti-inflammatory effect in rheumatoid arthritis (RA). High-capacity loading and a sustained release of target drugs were achieved by r...

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Bibliographic Details
Main Authors: Sang Jun Kim, Youngbo Choi, Khee Tae Min, Surin Hong
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
anti-inflammatory
drug delivery
loading efficiency
rheumatoid arthritis
silica nanoparticles
sustained release
Online Access:https://www.mdpi.com/1999-4923/14/5/985

Internet

https://www.mdpi.com/1999-4923/14/5/985

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