Tumour necrosis factor -308 and -238 promoter polymorphisms are predictors of a null virological response in the treatment of Brazilian hepatitis C patients

Certain host single nucleotide polymorphisms (SNPs) affect the likelihood of a sustained virological response (SVR) to treatment in subjects infected with hepatitis C virus (HCV). SNPs in the promoters of interleukin (IL)-10 (-1082 A/G, rs1800896), myxovirus resistance protein 1 (-123 C/A, rs1700090...

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Main Authors: Tarciana Grandi, Cláudia Maria Dornelles da Silva, Karine Medeiros Amaral, Paulo Dornelles Picon, Cintia Costi, Nicole Nascimento da Fré, Marilu Fiegenbaum, Tatiana Schäffer Gregianini, Christian Niel, Maria Lucia Rosa Rossetti
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2014-06-01
Series:Memorias do Instituto Oswaldo Cruz
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300345&lng=en&tlng=en