The Drosophila speciation factor HMR localizes to genomic insulator sites.

Hybrid incompatibility between Drosophila melanogaster and D. simulans is caused by a lethal interaction of the proteins encoded by the Hmr and Lhr genes. In D. melanogaster the loss of HMR results in mitotic defects, an increase in transcription of transposable elements and a deregulation of hetero...

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Bibliographic Details
Main Authors: Thomas Andreas Gerland, Bo Sun, Pawel Smialowski, Andrea Lukacs, Andreas Walter Thomae, Axel Imhof
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5312933?pdf=render