Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing

Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing

Abstract Background Plasmodium vivax poses a significant challenge to malaria elimination due to its ability to cause relapsed infections from reactivation of dormant liver parasites called hypnozoites. We analyzed 69 P. vivax whole genome sequences obtained from subjects residing in three different...

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Bibliographic Details
Main Authors: Annie N. Cowell, Hugo O. Valdivia, Danett K. Bishop, Elizabeth A. Winzeler
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Medicine
Subjects:
Malaria
Plasmodium vivax
Relapse
Primaquine
Whole genome sequencing
Population genetics
Online Access:http://link.springer.com/article/10.1186/s13073-018-0563-0

Internet

http://link.springer.com/article/10.1186/s13073-018-0563-0

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