Quality Improvement of Capsular Polysaccharide in Streptococcus pneumoniae by Purification Process Optimization

Streptococcus pneumoniae is the causative agent of many diseases, most notably pneumonia. Most of the currently used vaccines to protect against this pathogen employ pneumococcal capsular polysaccharides (CPSs) as antigens, but purifying CPS of sufficient quality has been challenging. A purification...

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Bibliographic Details
Main Authors: Chankyu Lee, Hee Jin Chun, Minchul Park, Rock Ki Kim, Yoon Hee Whang, Seuk Keun Choi, Yeong Ok Baik, Sung Soo Park, Inhwan Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00039/full