On which evidence can we rely when prescribing off-label methotrexate in dermatological practice? – a systematic review with GRADE approach

If an authorized drug is prescribed for a use that is not described in the Summary of Product Characteristics, this is defined as ‘off-label use.’ Methotrexate is often used off-label for dermatological indications. Off-label use is permitted if physicians can justify the treatment based on scientif...

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Bibliographic Details
Main Authors: Astrid M. van Huizen, Francisca M. Vermeulen, Cathelijne M. J. M. Bik, Rinke Borgonjen, Saskia A. T. Karsch, Rosanna A. Kuin, Louise A. A. Gerbens, Phyllis I. Spuls
Format: Article
Language:English
Published: Taylor & Francis Group 2022-05-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2021.1961999