RNF43 is associated with genomic features and clinical outcome in BRAF mutant colorectal cancer

RNF43 is associated with genomic features and clinical outcome in BRAF mutant colorectal cancer

BackgroundColorectal cancer (CRC) patients with BRAF mutation have very poor prognosis. It is urgent to search for prognostic factors of BRAF mutant CRC. RNF43 is a ENF ubiquitin ligase of Wnt signaling. Mutation of RNF43 has been observed frequently in various types of human cancers. However, few s...

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Bibliographic Details
Main Authors: Peipei Shang, Jiongjiong Lu, Feihong Song, Yijun Zhao, Weipeng Hong, Yuange He, Weidong Shen, Li Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
RNF43
BRAF
genomic features
clinical outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1119587/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1119587/full

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