Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T
Abstract NADH and NAD+ act as electron donors and acceptors and NAD+ was shown to stimulate mitochondrial biogenesis and metabolic health. We here develop a non-invasive Phosphorous Magnetic Resonance Spectroscopy (31P-MRS) method to quantify these metabolites in human skeletal muscle on a clinical...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-53292-4 |