Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome

Abstract Trypanosoma brucei causes human African trypanosomiasis (HAT) and nagana in cattle. During infection of a vertebrate, endocytosis of host transferrin (Tf) is important for viability of the parasite. The majority of proteins involved in trypanosome endocytosis of Tf are unknown. Here we iden...

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Bibliographic Details
Main Authors: Gaurav Kumar, Bryanna Thomas, Kojo Mensa-Wilmot
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22054-x