Association of cholesteryl ester transfer protein with HDL particles reduces its proteolytic inactivation by mast cell chymase

Association of cholesteryl ester transfer protein with HDL particles reduces its proteolytic inactivation by mast cell chymase

Human atherosclerotic intima contains mast cells that secrete the neutral protease chymase into the intimal fluid, which also contains HDL-modifying proteins, such as cholesteryl ester transfer protein (CETP), in addition to abundant amounts of nascent discoidal HDL particles. Here, we studied chyma...

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Bibliographic Details
Main Authors: Miriam Lee-Rueckert, Riikka Vikstedt, Jari Metso, Matti Jauhiainen, Petri T. Kovanen
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Journal of Lipid Research
Subjects:
proteolysis
cholesterol efflux
reverse cholesterol transport
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428561

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http://www.sciencedirect.com/science/article/pii/S0022227520428561

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