Transplanted human induced pluripotent stem cells- derived retinal ganglion cells embed within mouse retinas and are electrophysiologically functional

Summary: Glaucoma is an optic neuropathy characterized by permanent visual field loss caused by the death of retinal ganglion cells (RGCs) and it is the leading cause of irreversible blindness worldwide. Consequently, there is an unmet need for the development of new strategies for its treatment. We...

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Bibliographic Details
Main Authors: Vrathasha Vrathasha, Sergei Nikonov, Brent Allen Bell, Jie He, Yajat Bungatavula, Katherine Elizabeth Uyhazi, Venkata Ramana Murthy Chavali
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222015802