Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives

We selectively oxidized the C-23 hydroxyl group in an asiatic acid (AA) derivative and then, for the first time with AA, modification of the C-23 carboxyl group was conducted to synthesize a series of new AA derivatives. The evaluation of their cytotoxic activities against two human cancer cell line...

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Bibliographic Details
Main Authors: Yi-hong Lu, Ming-cang Chen, Fang Liu, Zhou Xu, Xiao-ting Tian, Yang Xie, Cheng-gang Huang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/16/3709