ACKR4 in Tumor Cells Regulates Dendritic Cell Migration to Tumor-Draining Lymph Nodes and T-Cell Priming

ACKR4 in Tumor Cells Regulates Dendritic Cell Migration to Tumor-Draining Lymph Nodes and T-Cell Priming

Colorectal cancer (CRC) is one of the most common malignancies in both morbidity and mortality. Immune checkpoint blockade (ICB) treatments have been successful in a portion of mismatch repair-deficient (dMMR) CRC patients but have failed in mismatch repair-proficient (pMMR) CRC patients. Atypical C...

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Bibliographic Details
Main Authors: Dechen Wangmo, Prem K. Premsrirut, Ce Yuan, William S. Morris, Xianda Zhao, Subbaya Subramanian
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
colorectal cancer
immune checkpoints
dendritic cells
Atypical Chemokine Receptor 4 (ACKR4)
T-cell priming
immune checkpoint blockade
Online Access:https://www.mdpi.com/2072-6694/13/19/5021

Internet

https://www.mdpi.com/2072-6694/13/19/5021

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