Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors

Abstract There is limited knowledge of the biology of breast cancer (BC) brain metastasis (BM). We primarily aimed to determine the mutations in BCBM and to compare the mutational pattern with the matched primary breast cancer (BC). Secondary aims were to determine mutations in each subgroup (Lumina...

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Bibliographic Details
Main Authors: Anna Thulin, Carola Andersson, Elisabeth Werner Rönnerman, Shahin De Lara, Chaido Chamalidou, Arnd Schoenfeld, Anikó Kovács, Henrik Fagman, Fredrik Enlund, Barbro K. Linderholm
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02903-x