The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore

The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore

Kinetochores are macromolecular protein complexes at centromeres that ensure accurate chromosome segregation by attaching chromosomes to spindle microtubules and integrating safeguard mechanisms. The inner kinetochore is assembled on CENP-A nucleosomes and has been implicated in establishing a kinet...

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Bibliographic Details
Main Authors: Josef Fischböck-Halwachs, Sylvia Singh, Mia Potocnjak, Götz Hagemann, Victor Solis-Mezarino, Stephan Woike, Medini Ghodgaonkar-Steger, Florian Weissmann, Laura D Gallego, Julie Rojas, Jessica Andreani, Alwin Köhler, Franz Herzog
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
kinetochore
mass spectrometry
feedback control
chromosome segregation
chemical crosslinking
error correction
Online Access:https://elifesciences.org/articles/42879

Internet

https://elifesciences.org/articles/42879

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