A Pentavalent <i>Shigella flexneri</i> LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models

A multivalent vaccine is much needed to achieve protection against predominant <i>Shigella</i> serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated <i>S. flexneri</i> 2a lipopolysaccharide (Ac<sub>3</sub>-S-LPS)...

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Bibliographic Details
Main Authors: Vladimir A. Ledov, Marina E. Golovina, Biana I. Alkhazova, Vyacheslav L. Lvov, Alexander L. Kovalchuk, Petr G. Aparin
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/2/345