The Impact of Exposure Profile on the Efficacy of Dual Amylin and Calcitonin Receptor Agonist Therapy

The Impact of Exposure Profile on the Efficacy of Dual Amylin and Calcitonin Receptor Agonist Therapy

Background: Dual Amylin and Calcitonin Receptor Agonists (DACRAs) are treatment candidates for obesity and type 2 diabetes. Recently, a once-weekly DACRA (KBP-A) showed promise, potentially due to its different exposure profile compared to daily DACRA (KBP). Parathyroid hormone, a G-protein-coupled...

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Bibliographic Details
Main Authors: Nina Sonne, Anna Thorsø Larsen, Morten Asser Karsdal, Kim Henriksen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
DACRA
GPCR
obesity
type 2 diabetes
preclinical
Online Access:https://www.mdpi.com/2227-9059/10/10/2365

Internet

https://www.mdpi.com/2227-9059/10/10/2365

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