Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression

Key proteins of invadopodia are overexpressed in oral squamous cell carcinoma suggesting an important role of MT1-MMP in the tumoral progression

Abstract Background Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis. Tumour invasion and metastasis that affect prognosis are result of a set of complex events that cells with invasive p...

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Bibliographic Details
Main Authors: Geovanni Pereira Mitre, Karolyny Martins Balbinot, André Luis Ribeiro Ribeiro, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Diagnostic Pathology
Subjects:
Oral squamous cell carcinoma
Immunohistochemistry
Invadopodia
Neoplasm Invasiveness
Pathology
Online Access:https://doi.org/10.1186/s13000-021-01090-7

Internet

https://doi.org/10.1186/s13000-021-01090-7

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