Evaluation of imputation performance of multiple reference panels in a Pakistani population

Evaluation of imputation performance of multiple reference panels in a Pakistani population

Summary: Genotype imputation is crucial for genome-wide association studies (GWASs), but reference panels and existing benchmarking studies prioritize European individuals. Consequently, it is unclear which publicly available reference panel should be used for Pakistani individuals, and whether ance...

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Bibliographic Details
Main Authors: Jiayi Xu, Dongjing Liu, Arsalan Hassan, Giulio Genovese, Alanna C. Cote, Brian Fennessy, Esther Cheng, Alexander W. Charney, James A. Knowles, Muhammad Ayub, Roseann E. Peterson, Tim B. Bigdeli, Laura M. Huckins
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:HGG Advances
Subjects:
Genetics
genome-wide association studies
imputation
imputation panels
South Asian ancestry
Pakistan
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247724001350

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http://www.sciencedirect.com/science/article/pii/S2666247724001350

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