Comprehensive microbiomes and fecal metabolomics combined with network pharmacology reveal the effects of Jichuanjian on aged functional constipation

Comprehensive microbiomes and fecal metabolomics combined with network pharmacology reveal the effects of Jichuanjian on aged functional constipation

Background: Functional constipation is a common gastrointestinal disorder especially severely affecting the life quality of the aged. Jichuanjian (JCJ) has been widely used for aged functional constipation (AFC) in clinic. Yet, the mechanisms of JCJ merely scratch the surface with being studied at a...

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Bibliographic Details
Main Authors: Xiaojie Liu, Ziyu Zhao, Di Zhao, Sijun Zhao, Xuemei Qin
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Experimental Gerontology
Subjects:
Aged functional constipation
Jichuanjian
Metabolomics
Microbiomes
“Behaviors-intestinal bacteria-metabolites” inter- and inner-layer networks
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523001377

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http://www.sciencedirect.com/science/article/pii/S0531556523001377

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