Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation

IntroductionFood allergy is a significant public health problem with limited treatment options. As Food Allergy Herbal Formula 2 (FAHF-2) showed potential as a food allergy treatment, we further developed a purified version named EBF-2 and identified active compounds. We investigated the mechanisms...

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Main Authors: Nan Yang, Anish R. Maskey, Kamal Srivastava, Monica Kim, Zixi Wang, Ibrahim Musa, Yanmei Shi, Yixuan Gong, Ozkan Fidan, Julie Wang, David Dunkin, Danna Chung, Jixun Zhan, Mingsan Miao, Hugh A. Sampson, Xiu-Min Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1081121/full