Are Induced Pluripotent Stem Cells a Step towards Modeling Pediatric Leukemias?

Are Induced Pluripotent Stem Cells a Step towards Modeling Pediatric Leukemias?

Despite enormous improvements in pre-clinical and clinical research, acute leukemia still represents an open challenge for pediatric hematologists; both for a significant relapse rate and for long term therapy-related sequelae. In this context, the use of an innovative technology, such as induced pl...

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Bibliographic Details
Main Authors: Salvatore Nicola Bertuccio, Davide Leardini, Daria Messelodi, Laura Anselmi, Francesca Manente, Federico Ragni, Salvatore Serravalle, Riccardo Masetti, Andrea Pession
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
pediatric leukemia
in vitro modeling
iPSCs
genome editing
new target therapies
Online Access:https://www.mdpi.com/2073-4409/11/3/476

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https://www.mdpi.com/2073-4409/11/3/476

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