Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo.

Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo.

Several studies have indicated that inflammation during pregnancy increases the risk for the development of neuropsychiatric disorders in the offspring. Morphological brain abnormalities combined with deviations in the inflammatory status of the brain can be observed in patients of both autism and s...

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Bibliographic Details
Main Authors: Silke eSmolders, Sophie MT Smolders, Nina eSwinnen, Annette eGärtner, Jean-Michel eRigo, Pascal eLegendre, Bert eBrône
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Microglia
Cortex
embryo
neuropsychiatric disorders
maternal immune activation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00301/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00301/full

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