Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma

Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma

Recent transcriptomic-based analysis of diffuse large B cell lymphoma (DLBCL) has highlighted the clinical relevance of LN fibroblast and tumor-infiltrating lymphocyte (TIL) signatures within the tumor microenvironment (TME). However, the immunomodulatory role of fibroblasts in lymphoma remains uncl...

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Xehetasun bibliografikoak
Egile Nagusiak: Benedetta Apollonio, Filomena Spada, Nedyalko Petrov, Domenico Cozzetto, Despoina Papazoglou, Peter Jarvis, Shichina Kannambath, Manuela Terranova-Barberio, Rose-Marie Amini, Gunilla Enblad, Charlotte Graham, Reuben Benjamin, Elisabeth Phillips, Richard Ellis, Rosamond Nuamah, Mansoor Saqi, Dinis P. Calado, Richard Rosenquist, Lesley A. Sutton, Jon Salisbury, Georgios Zacharioudakis, Anna Vardi, Patrick R. Hagner, Anita K. Gandhi, Marina Bacac, Christina Claus, Pablo Umana, Ruth F. Jarrett, Christian Klein, Alexander Deutsch, Alan G. Ramsay
Formatua: Artikulua
Hizkuntza:English
Argitaratua: American Society for Clinical Investigation 2023-07-01
Saila:The Journal of Clinical Investigation
Gaiak:
Immunology
Oncology
Sarrera elektronikoa:https://doi.org/10.1172/JCI166070

Internet

https://doi.org/10.1172/JCI166070

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