Re-directing CD4+ T cell responses with the flanking residues of MHC class II-bound peptides: the core is not enough

Re-directing CD4+ T cell responses with the flanking residues of MHC class II-bound peptides: the core is not enough

Recombinant αβ T cell receptors (TCRs) recognise short peptides presented at the cell surface in complex with MHC molecules. There are two main subsets of αβ T cells: CD8+ T cells that recognise mainly cytosol-derived peptides in the context of MHC class I (pMHC-I), and CD4+ T cells that recognise p...

Full description

Bibliographic Details
Main Author: David Kenneth Cole
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
crystal structure
Vaccine
T cell
influenza
T cell receptor (TCR)
surface plasmon resonance (SPR)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00172/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00172/full

Similar Items