Rotten to the core: antivirals targeting the HIV-1 capsid core

Abstract The capsid core of HIV-1 is a large macromolecular assembly that surrounds the viral genome and is an essential component of the infectious virus. In addition to its multiple roles throughout the viral life cycle, the capsid interacts with multiple host factors. Owing to its indispensable n...

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Bibliographic Details
Main Authors: William M. McFadden, Alexa A. Snyder, Karen A. Kirby, Philip R. Tedbury, Monika Raj, Zhengqiang Wang, Stefan G. Sarafianos
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Retrovirology
Online Access:https://doi.org/10.1186/s12977-021-00583-z