Semaphorin 6C Suppresses Proliferation of Pancreatic Cancer Cells via Inhibition of the AKT/GSK3/β-Catenin/Cyclin D1 Pathway

Semaphorin 6C Suppresses Proliferation of Pancreatic Cancer Cells via Inhibition of the AKT/GSK3/β-Catenin/Cyclin D1 Pathway

Semaphorins (SEMAs) are axon guidance factors that participate in axonal connections and nerve system development. However, the functional roles of SEMAs in tumorigenesis are still largely uncovered. By using in silico data analysis, we found that SEMA6C was downregulated in pancreatic cancer, and i...

Full description

Bibliographic Details
Main Authors: Yu-Hsuan Hung, Shih-Han Hsu, Ya-Chin Hou, Pei-Yi Chu, Yung-Yeh Su, Yan-Shen Shan, Wen-Chun Hung, Li-Tzong Chen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
SEMA6C
CDK4/6
pancreatic cancer
Online Access:https://www.mdpi.com/1422-0067/23/5/2608

Internet

https://www.mdpi.com/1422-0067/23/5/2608

Similar Items